Various flora have been in a push and pull balance with fauna for hundreds of millions of years. I find it more likely that something whose very reproductive cycle depends on being eaten by animals is the healthier alternative to something engineered for a singular purpose without long-term testing on humans.

I was once a multiple-a-day energy drink consumer. The fizzy caffeine+sugar+choline+inositol mixture in a can has barely been around a few decades. Do you know what compounds the artificial flavors are? I've since switched to getting my caffeine from plants. It's been verified by a plethora of civilizations over thousands years.